NUR 2349 Professional Nursing I

PN1 Exam 3 Study Guide

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First line of defense against infection

- innate immunity

(skin, mucus membrane, stomach acid... etc.)

Second line of defense against infection

- nonspecific resistance

Last line of defense against infection

- antibody-medicated immunity

Common labs for infection and inflammation

- ESR, CRP, PV

Hemostasis phase

- occurs immediately after injury

- liquid called exudate is made up of plasma and blood

- blood vessels constrict

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Inflammatory phase

- Last about 4 to 6 days

- White blood cells move toward wound

- pt have mildly elevated body temp and increase in WBCS

Proliferative phase

- new tissue built

- last several weeks

- adequate nutrition and oxygenation are important

Maturation phase

- Final stage of healing begins about 3 weeks to 6 months after injury.

- Collagen is remodeled.

- New collagen tissue is deposited.

- Scar becomes a flat, thin, white line.

Skin integrity

- condition of the skin

Class 1 wound

- clean wounds

1-5% infection rate

Class 2 wounds

- clean-contaminated

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