NUR 2063 Essentials of Pathophysiology
Pathophysiology Module 1 – 3 Exam Review
What are mediators of inflammation?
- histamine, bradykinins, complement, clotting factors, cytokines, chemokines
events in inflammation
- increased vascular permeability and fluid shift, emigration of leukocytes, phagocytosis
rapid hypersensitivity reaction
- allergies, anaphylaxis, sneezing. Mediated by igE antibodies
type 2 cytotoxic hypersensitivity
- autoimmune destruction as a result of IgG or IgM binding with antigen. hemolytic
disease of a new born or if someone gets a blood transfusion from someone of a
different blood type
Type 3 hypersensitivity reaction
- immune complex, example is autoimmune disease like lupus or rheumatoid arthritis
Type 4 hypersensitivity reaction, Delayed reaction
- T-cell mediated disorders like TB test
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