Pharmacology ATI Practice Questions
1. A nurse is preparing to administer warfarin to a client who has a new onset of
atrial fibrillation. The client asks the nurse, “What does this medication do?”
Which of the following responses should the nurse make?
a. “It helps your heart return to a normal rhythm.”
b. “It dissolves blood clots.”
c. “It can reduce your risk of having a stroke.”
d. “It helps to prevent bleeding in atrial fibrillation.”
Rationale: C. The nurse should identify that atrial fibrillation increases the
client’s risk of having a stroke due to clot formation in the atrium. Warfarin
can prevent clot formation when used long term, which will reduce the
client’s risk of having a stroke.
2. A nurse is caring for a client who has diabetes insipidus. Which of the
following laboratory values should the nurse identify as reflecting a
contraindication to receiving vasopressin to treat this disorder?
a. Sodium 152 mEq/L
b. Potassium 6.0 mEq/L
c. Creatinine clearance 50 mL/min
d. Aspartate aminotransferase (AST) 52 units/L
Rationale: C. Creatinine clearance should be above 87 mL/min for female
clients and above 107 mL/min for male clients. A creatinine clearance of 50
mL/min indicates renal impairment and is a contraindication to receiving
vasopressin. Renal impairment increases the likelihood of the lifethreatening adverse effect of water intoxication
3. A nurse is reviewing the medication history of a client who has mild
intermittent asthma. The nurse should anticipate a prescription for which of the
following inhalers for the client?
a. Ipratropium
b. Albuterol sulfate
c. Tiotropium
d. Budesonide
Rationale: B. The nurse should anticipate a client who has mild intermittent
asthma to be prescribed albuterol sulfate. Albuterol sulfate is a short acting
beta2-agonist that activates beta2-receptors in the smooth muscle of the
lung, allowing the client’s airway and lungs to dilate, thereby relieving
bronchospasm and allowing the client to breathe.
4. A nurse is caring for a client who has a dry nonproductive cough. Which of the
following types of medication should the nurse recommend?
a. Expectorant
b. Mucolytic
c. Bronchodilator
d. Antitussive
Rationale: D. Antitussives suppress the cough reflex. Expectorants help
mobilize secretions. Mucolytics help liquefy secretions.
5. A nurse is caring for a client who has heart failure and is taking oral furosemide
40 mg daily. For which of the following adverse effects should the client be
taught to monitor and notify the provider if it occurs?
a. Nasal congestion
b. Tremors
c. Tinnitus
d. Frontal headache
Rationale: C. Loop diuretics such as furosemide can cause ototoxicity. The
client should be taught to notify the provider if tinnitus, a full feeling in the
ears, or hearing loss occurs.
6. A nurse is monitoring a client who is receiving terbutaline to suppress preterm
labor. Which of the following findings should indicate to the nurse that the
client is experiencing an adverse effect of the medication?
a. BP 132/84 mmHg
b. Blood glucose 106 mg/dL
c. Decreased deep tendon reflexes
d. Maternal heart rate >120/min
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