NUR 2407 Pharmacology-Rasmussen College-Pham Exam I Study Guide NUR 2407 Pharmacology-Rasmussen College-Pham Exam I Study Guide Drugs that PRODUCE a response? o Agonist  Drugs that PREVENT a response? o Antagonist  Therapeutic WINDOW is what? o Level of the drug between minimal effective concentration in the plasma for obtaining desired drug response and the minimal toxic concentration  The time it takes for ½ of the drug concentration to be eliminated from the body is called? o Half life  What is a patient on two highly protein bound drugs at risk for o Accumulation and toxicity o A decreased responsiveness over the course of therapy which may lead to the need to increase dosages to attain the same effect tolerance