Chapter 48- Drugs Affecting Blood Coagulation

1. A patient is admitted to the hospital with deep vein thrombosis. Heparin 10,000 units is

administered Sub-Q. Which of the following drugs should always be available in the

pharmacy if the patient begins to bleed?

A) Antithrombin (Thrombate III)

B) Desirudin (Iprivask)

C) Protamine sulfate

D) Vitamin K

2. Prior to beginning anticoagulant therapy the nurse will question their female patient

about what?

A) Last menstrual period

B) Peptic ulcers

C) Urinary tract infection

D) Weight

3. You are caring for a mother who is nursing her 3-month-old infant. The mother requires

an anticoagulant after a venous thrombosis. What will the nurse instruct the mother to

do?

A) Wait an hour after taking the anticoagulant before feeding the infant

B) Push fluids to clear the drug from her system before feeding the infant

C) Find another method of feeding the infant while on this drug

D) Feed the infant before taking the anticoagulant

4. You work in the Emergency Department (ED) of a small rural hospital. A 54-year-old

man arrives in your ED and it is determined that he is having an acute myocardial

infarction. Before transferring the patient to a larger facility that has a heart

catheterization laboratory, what drug will you administer?

A) Anagrelide (Agrylin)

B) Clopidogrel (Plavix)

C) Ticlopidine (Ticlid)

D) Streptokinase (Streptase)

5. A nurse is preparing to discharge a patient newly prescribed warfarin (Coumadin).

While assessing the patient's knowledge of their drug, what would indicate that the

patient needs further instruction concerning her drug therapy?

A) “I love to eat homegrown tomatoes in the summer.”

B) “I take aspirin for my arthritis.”

C) “I walk two miles a day.”

D) “I drink a glass of wine about once a week.”

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6. The physiology instructor is discussing blood clots. What would the instructor tell the

students is the basis for the clot-dissolving system?

A) Hageman factor

B) Thrombin

C) Plasminogen

D) Fibrinolysin

7. You are caring for a patient who is on thrombolytic therapy. The patient has a comorbidity of renal insufficiency. What do you know about the amount of heparin

required to treat this patient?

A) You cannot use heparin to treat this patient

B) You do not need to use an infusion pump for this patient

C) Lower doses are required

D) Higher doses are required

8. A patient is being discharged home on warfarin. The discharge teaching by the nurse

should include a warning to avoid what?

A) St. John's wort

B) Tarragon

C) Ginkgo

D) Saw palmetto

9. Clopidogrel (Plavix) is used frequently for what?

A) Maintaining the patency of grafts

B) Treatment of peripheral artery disease

C) Preventing emboli from valve replacements

D) Dissolving a pulmonary embolus and improving oxygenation

10. You are caring for a patient who is going home on warfarin (Coumadin). You will

schedule the patient for what following laboratory tests to help evaluate therapeutic

effects of the drug?

A) Prothrombin time (PT) only

B) International normalized ratio (INR) only

C) Prothrombin time (PT) and international normalized ratio (INR)

D) Prothrombin time (PT) and activated partial thromboplastin time (APTT)

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