Clayton's Basic Pharmacology for

Nurses, 18th Edition

by Michelle J. Willihnganz, MS, RN, CNE,

Samuel L. Gurevitz, PharmD, CGP and

Bruce D. Clayton

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TABLE OF CONTENTS.

Unit 1: Applying Pharmacology to Nursing Practice

1. Drug Definitions, Standards, and Information Sources

2. Basic Principles of Drug Action and Drug Interactions

3. Drug Action Across the Life Span

4. The Nursing Process and Pharmacology

5. Patient Education to Promote Health

Unit 2: Illustrated Atlas of Medication Administration

6. Principles of Medication Administration and Medication Safety

7. Percutaneous Administration

8. Enteral Administration

9. Parenteral Administration: Safe Preparation of Parenteral Medications

10. Parenteral Administration: Intradermal, Subcutaneous, and Intramuscular Routes

11. Parenteral Administration: Intravenous Route

Unit 3: Drugs Affecting the Autonomic and Central Nervous Systems

12. Drugs Affecting the Autonomic Nervous System

13. Drugs Used for Sleep

14. Drugs Used for Neurodegenerative Disorders (NEW!)

15. Drugs Used for Anxiety Disorders

16. Drugs Used for Depressive and Bipolar Disorders

17. Drugs Used for Psychoses

18. Drugs Used for Seizure Disorders

19. Drugs Used for Pain Management

Unit 4: Drugs Affecting the Cardiovascular System

20. Introduction to Cardiovascular Disease and Metabolic Syndrome

21. Drugs Used to Treat Dyslipidemias

22. Drugs Used to Treat Hypertension

23. Drugs Used to Treat Dysrhythmias

24. Drugs Used to Treat Angina Pectoris

25. Drugs Used to Treat Peripheral Vascular Disease

26. Drugs Used to Treat Thromboembolic Disorders

27. Drugs Used to Treat Heart Failure

28. Drugs Used for Diuresis

Unit 5: Drugs Affecting the Respiratory System

29. Drugs Used to Treat Upper Respiratory Disease

30. Drugs Used to Treat Lower Respiratory Disease

Unit 6: Drugs Affecting the Digestive System

31. Drugs Used to Treat Oral Disorders

32. Drugs Used to Treat Gastroesophageal Reflux and Peptic Ulcer Disease

33. Drugs Used to Treat Nausea and Vomiting

34. Drugs Used to Treat Constipation and Diarrhea

Unit 7: Drugs That Affect the Endocrine System

35. Drugs Used to Treat Diabetes Mellitus

36. Drugs Used to Treat Thyroid Disease

37. Corticosteroids

38. Gonadal Hormones

Unit 8: Drugs Affecting the Reproductive System

39. Drugs Used in Obstetrics

40. Drugs Used in Men’s and Women’s Health

Unit 9: Drugs Affecting Other Body Systems

41. Drugs Used to Treat Disorders of the Urinary System

42. Drugs Used to Treat Glaucoma and Other Eye Disorders

43. Drugs Used to Treat Cancer 44. Drugs Used to Treat the Musculoskeletal System

45. Drugs Used to Treat Infection

Unit 10: Drugs Affecting the General Health of the Body

46. Nutrition

47. Herbal and Dietary Supplemental Therapy

48. Substance Abuse

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Chapter 1: Drug Definitions, Standards, and Information SourcesTest Bank

MULTIPLE CHOICE

1. What is the name under which a drug is listed by the U.S. Food and Drug Administration

(FDA)?

a. Brand

b. Nonproprietary

c. Official

d. Trademark

ANS: C

The official name is the name under which a drug is listed by the FDA. The brand name, or

trademark, is the name given to a drug by its manufacturer. The nonproprietary, or generic,

name is provided by the U.S. Adopted Names Council.

DIF: Cognitive Level: Knowledge REF: p. 1 OBJ: 2

TOP: Nursing Process Step: Assessment

MSC: NCLEX Client Needs Category: Safe, Effective Care Environment

2. Which source contains information specific to nutritional supplements?

a. USP Dictionary of USAN & International Drug Names

b. Natural Medicines Comprehensive Database

c. United States Pharmacopoeia/National Formulary (USP NF)

d. Drug Interaction Facts

ANS: C

United States Pharmacopoeia/National Formulary contains information specific to nutritional

supplements. USP Dictionary of USAN & International Drug Names is a compilation of drug

names, pronunciation guide, and possible future FDA approved drugs; it does not include

nutritional supplements. Natural Medicines Comprehensive Database contains evidence based

information on herbal medicines and herbal combination products; it does not include

information specific to nutritional supplements. Drug Interaction Facts contains

comprehensive information on drug interaction facts; it does not include nutritional

supplements.

DIF: Cognitive Level: Knowledge REF: p. 2 OBJ: 4

TOP: Nursing Process Step: Assessment

MSC: NCLEX Client Needs Category: Physiological Integrity

3. What is the most comprehensive reference available to research a drug interaction?

a. Drug Facts and Comparisons

b. Drug Interaction Facts

c. Handbook on Injectable Drugs

d. Martindale—The Complete Drug Reference

ANS: B

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First published in 1983, Drug Interaction Facts is the most comprehensive book available on

drug interactions. In addition to monographs listing various aspects of drug interactions, this

information is reviewed and updated by an internationally renowned group of physicians and

pharmacists with clinical and scientific expertise.

DIF: Cognitive Level: Comprehension REF: p. 3 OBJ: 3

TOP: Nursing Process Step: Assessment

MSC: NCLEX Client Needs Category: Physiological Integrity

4. The physician has written an order for a drug with which the nurse is unfamiliar. Which

section of the Physicians’ Desk Reference (PDR) is most helpful to get information about this

drug?

a. Manufacturer‟ssection

b. Brand and Generic Name section

c. Product Category section

d. Product Information section

ANS: B

A physician‟s order would include the brand and/or generic name of the drug. The alphabetic

index in the PDR would make this section the most user friendly. Based on a physician‟s

order, manufacturer‟s information and classification information would not be known. The

Manufacturer‟s section is a roster of manufacturers. The Product Category section lists

products subdivided by therapeutic classes, such as analgesics, laxatives, oxytocics, and

antibiotics. The Product Information section contains reprints of the package inserts for the

major products of manufacturers.

DIF: Cognitive Level: Comprehension REF: p. 3 OBJ: 4

TOP: Nursing Process Step: Planning

MSC: NCLEX Client Needs Category: Physiological Integrity

5. Which online drug reference makes available to health care providers and the public a

standard, comprehensive, up to date look up and downloadable resource about medicines?

a. American Drug Index

b. American Hospital Formulary

c. DailyMed

d. Physicians’ Desk Reference (PDR)

ANS: C

DailyMed makes available to health care providers and the public a standard, comprehensive,

up to date look up and downloadable resource about medicines. The American Drug Index is

not appropriate for patient use. The American Hospital Formulary is not appropriate for

patient use. The PDR is not appropriate for patient use.

DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: 5

TOP: Nursing Process Step: Implementation

MSC: NCLEX Client Needs Category: Physiological Integrity

6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?

a. Federal Food, Drug, and Cosmetic Act (1938)

b. Durham Humphrey Amendment (1952)

c. Controlled Substances Act (1970)

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