BSC 2347 Human Anatomy and Physiology II

Anatomy & Physiology II: Module 01 Q & A

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Majority of clotting factors are plasma proteins produced where?

In the liver

What is hemostasis dependent upon?

Thrombocytes and fibrinogen

What is required for the production of 4 clotting factors?

Vitamin K

What is the ultimate goal of coagulation?

To convert plasma protein fibrinogen into fibrin threads to produce a crosslinked

fibrin mesh

What is the intrinsic pathway of coagulation?

Blood vessel damage

What is the extrinsic pathway of coagulation?

Tissue and cell trauma 

What is the final common pathway of coagulation?

Thrombin activates CF XIII into its active form and binds the fibrin threads tightly

together

Fibrinolysis

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Process that removes unneeded clots when the healing process has completed

What is plasmin?

The enzyme that breaks down and digests the clot

Anticoagulants

Factors that inhibit the clotting process

Thrombus

Abnormal/unwanted clot formation in a vessel that is not damaged

Embolus

When a portion or all of a thrombus breaks away and travels elsewhere in the body

Embolism

When the embolus lodges in smaller blood vessel and blocks blood flow

Hemophilia

Hereditary bleeding disorder

Hemophilia A is the most common bleeding disorder as a result of deficiency in?

CF VIII 

Thrombocytopenia

Deficient amounts of platelets in circulation

Impaired liver function

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Can cause bleeding disorders due to reduction of production of CF

What is ABO Blood Typing dependent upon?

Antigens found on the surface of erythrocytes

What are antigens also referred to as?

Agglutinogens

Specific antibodies are present in the blood plasma according to the specific antigens on

the RBCs. Are you born with them or without them?

Without, but they develop over time.

What type of antibodies does blood type A have?

Anti-B antibodies

What type of antibodies does blood type AB have?

None

What type of antigens does type O have in the red blood cell?

None

What is the Rh factor?

Another antigen present or absent on the cell membrane of RBCs 

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