NUR 2474 Pharmacology for Professional Nursing

Module 10 Quiz Q & A Blueprint

1. Which trimester holds the highest risk for teratogenicity of drugs? First. Good

studies on teratogenicity are often not performed, as many are not ethical.

2. What are the FDA pregnancy risk categories? Are they evidence based?

Compare meds with these categories with your doctor.

3. Why do lipid-soluble drugs cross the placenta easily? They diffuse across the lipid

membrane quite easily. Which one will cross more readily, highly protein-bound or

low protein-bound drugs? Protein-bound means the drug is being “hugged” by the

protein; therefore, the greater it is bound, the less likely it is to cross the placenta.

The less likely it is bound, the more likely it will cross. Non-ionized drugs cross the

placenta more readily. Ionized drugs DO NOT cross the placenta readily.

4. All medications involve some sort of risk-benefit analysis. How do the benefits of

asthma therapy outweigh the risks of treatment? A baby’s health is dependent on

Mom. Controlled asthma leads to better support of baby.