A Norepinephrine

B GABA

.

C

Dopamine

.

D Acetylcholine

Answer:

Dopamine

Obsessive-compulsive disorder (OCD) is linked to defects in the cortico-striatal-thalamic-cortical (CSTC)

circuitry, which may be linked to neurotransmitter dysregulation throughout this network. Serotonin,

dopamine, glutamate, and -aminobutyric acid (GABA) are the main neurotransmitters throughout the

CSTC.

Compulsive behaviors linked to OCD are likely the product of a related dopaminergic reward

system dysfunction. Continuous ventral striatum activation may lead to an undirected expectation of

reward. Anxiety and a desire to fill the gap are caused by unfulfilled expectations.

Step-by-Step explanation

References

Richter, M. A., De Jesus, D. R., Hoppenbrouwers, S., Daigle, M., Deluce, J., Ravindran, L. N., ... &

Daskalakis, Z. J. (2019). Evidence for cortical inhibitory and excitatory dysfunction in obsessive

compulsive disorder. Neuropsychopharmacology, 37(5), 1144-1151.

Pittenger, C., Krystal, J. H., & Coric, V. (2016). Glutamate-modulating drugs as novel

pharmacotherapeutic agents in the treatment of obsessive-compulsive disorder. NeuroRx, 3(1), 69-81.

1 points

QUESTION 2

1. Select the class of drugs most effective in treating pain disorder.

Answer:

A Opioid analgesics

.

B TCA and SSRI

. antidepressants

C Beta-adrenergic

. blockers

D

Mood stabilizers

.

Opioids analgesics