Chapter 01: Introduction

Celentano: Gordis Epidemiology, 6th Edition

Test Bank

MULTIPLE CHOICE

1. Which of the following is an example of tertiary prevention?

a. Vaccination for rotavirus for children younger than the age of 1 year

b. Surgical amputation of an extremity with osteosarcoma (bone cancer)

c. Screening for gestational diabetes after 24 weeks of pregnancy

d. Sexual education program in elementary schools

e. Increasing taxes for buying cigarettes

ANS: B

Surgical amputation of an extremity with osteosarcoma (bone cancer) is an example in which

when a disease is present the treatment (amputation) is done to reduce the impact of disease

by preventing the tumor from dissemination. Vaccination for rotavirus for children younger

than the age of 1 year, sexual education program in elementary schools, and increasing taxes

for buying cigarettes represent examples of primary prevention. Screening for gestational

diabetes after 24 weeks of pregnancy is an example of secondary prevention.

2. This historic character observed that childbed fever mortality was more common among

women treated by physicians and medical students compared with women treated by

midwives. Based on his observations, he implemented a hand wash policy that resulted in a

decrease in mortality. Name the character that we are talking about.

a. John Snow

b. Edward Jenner

c. D.A. Henderson

d. Leon Gordis

e. Ignaz Semmelweis

ANS: E

Ignaz Semmelweis identified that medical students and physicians transmitted the disease by

not washing their hands after examining bodies at autopsies and conducting multiple

examinations in the clinic.

3. Thanks to the contributions of Edward Jenner, the following disease was eradicated later

by efforts organized by D.A. Henderson:

a. Cholera

b. Smallpox

c. Chickenpox

d. Polio

e. Zika

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Test Bank

Copyright © 2020 by Elsevier, Inc. All rights reserved.

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ANS: B

Smallpox was eradicated in 1980. Edward Jenner vaccinated James Phipps in 1796 against

smallpox. Almost 200 years later, the World Health Organization (WHO) commissioned

D.A. Henderson to lead the efforts to eradicate the disease.

4. Over the past century, a marked decline in the mortality rates of many infectious diseases

has been observed. Which of the following is the most likely reason for the observed decline

in mortality rates from common infectious diseases?

a. Development of penicillin

b. Development of insulin

c. Development of vaccines

d. Improvement in social conditions

e. Worse sanitation and unsafe water

ANS: D

Although medical treatments potentially helped in the decrease of infectious diseases, the

advancement in social conditions played a major role. These improvements include better

sanitation, safe disposal of waste, better nutrition, and improvement in housing conditions.

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Chapter 02: The Dynamics of Disease Transmission

Celentano: Gordis Epidemiology, 6th Edition

Test Bank

MULTIPLE CHOICE

1. Which term most accurately describes the following definition? “The occurrence in a

community or region of cases of an illness, specific health-related behavior, or other healthrelated events clearly in excess of normal expectancy.” [Porta M, ed. A Dictionary of

Epidemiology. New York: Oxford University Press; 2014.]

a. Endemic

b. Epidemic

c. Pandemic

d. Attack rate

e. Incubation period

ANS: B

An epidemic is the occurrence of health-related events in a community or region, in clear

excess of normal expectation. Endemic is not true because it is defined as the constant

occurrence of a disease, disorder, or noxious infectious agent in a geographic area or

population group. Pandemic is as an epidemic occurring over a

very wide area, crossing international boundaries, and usually affecting a large number of

people. Attack rate is not true because it is defined as number of people at risk in whom a

certain illness develops over total number of people at risk. Incubation period is not true

because it is the interval from receipt of infection to the time of onset of clinical illness (the

onset of recognizable symptoms).

2. What is the most accurate definition of the incubation period (of an infectious disease)?

a. The time of onset of clinical illness or the onset of recognizable symptoms

b. The interval from receipt of infection to the time of onset of clinical illness (the onset of

recognizable symptoms)

c. The time of invasion by an infectious agent

d. The time between initiation of infection and first shedding or excretion of the agent

e. The period between exposure and the onset of infectiousness

ANS: B

The incubation period is defined as the interval from receipt of infection to the time of onset

of clinical illness (the onset of recognizable symptoms); in other words, the time between the

moment of developing symptoms and the moment of invasion by an infectious agent. “The

time of onset of clinical illness or the onset of recognizable symptoms” is not true as it

corresponds to “time of onset.” “The time of invasion by an infectious agent” is not true as it

corresponds to “time of infection.” “The time between initiation of infection and first

shedding or excretion of the agent” and “The period between exposure and the onset of

infectiousness” are not true as they correspond to the latent period. (The latent period is

Copyright © 2020 by Elsevier, Inc. All rights reserved.

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Test Bank

Copyright © 2020 by Elsevier, Inc. All rights reserved.

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focusing on the onset of infectiousness, but the incubation period is focusing on the onset of

the symptom.)

3. There was a food poisoning outbreak on April 1, 2018, at the City Z Food Safety

Conference. There were 1,000 people registered for the conference with luncheon, 100

volunteers to host attendees, and 50 people who served the luncheon during the conference.

Except for 50 people who served the food, all of the participants and volunteers ate the food

from the luncheon at the conference on April 1, 2018. Based only on the information given in

this question, how many people are at risk in this food poisoning outbreak?

a. 1,000

b. 1,100

c. 1,150

d. 150

e. 50

ANS: B

People at risk in this outbreak are people who were exposed to the food at the conference.

Even though 1,150 people were at the conference, 50 people who served the food did not eat

the food. Therefore we have to exclude those 50 people.

4. There was a food poisoning outbreak on April 1, 2018, at the City Z Food Safety

Conference. There were 1,000 people registered for the conference with luncheon, 100

volunteers to host attendees, and 50 people who served the luncheon during the conference.

Except for 50 people who and volunteers ate the food from the luncheon at the conference

on April 1, 2018. After an initial outbreak of food poisoning is reported, an epidemiologist

sends surveys to all people at risk to investigate the cause. However, only 900 people among

those at risk answer the survey. After analysis of 900 survey results, the epidemiologist

concludes that the most suspected foods in the outbreak are pepperoni pizza and meatball

spaghetti. What is the overall attack rate for those who ate meatball spaghetti? Use the

following table to answer the question.

Summary of Survey Responses

Number of people who

developed the case definition

symptoms

Number of people who ate the

food

Pepperoni pizza only 113 275

Meatball spaghetti only 62 375

Both pepperoni pizza and

meatball spaghetti

57 150

Neither of pepperoni pizza or

meatball spaghetti

10 100

a. 41%

b. 38%

c. 27%

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