NUR 2407 Pharmacology

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Pharmacology Week 1 Quiz Rasmussen

Drug

- Any Chemical the Alters the Body

Pharmacology

- The study of the chemical, biological, and physiological effects of drugs

Clinical Pharmacology

- Studying the effects of drugs on humans

Therapeutics

- Studying the use of drugs to treat disease

The Big Three

- Effectiveness

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- Safety

- Selectivity 

Effectiveness

- Did it work

Safety

- A safe drug causes no harm

All drugs can be harmful

Selectivity

- A drug that only produces the desired effect

Factors that contribute to intensity of drugs in the body

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- •Gender

- •Ethnicity

- •Weight

- •Adipose tissue

- •Kidney Function

- •Liver Function

- •Age

- •Food/NPO

- •Dose

- •Genetics

- •½ life 

Determinants That Affect Drug Therapy

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Half-life (t½)-

- Time it takes for ½ of the drug concentration to be eliminated (affected by

metabolism and elimination)

Half Life Example

- •Example Pill A 10mg has half-life 2 hours

•0800: 10mg

•1000: 5mg

•1200: 2.5mg

•1400: 1.25mg etc. until completed eliminated 

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