NR507 / NR 507 Final Exam (Latest 2021): Advanced Pathophysiology - ChamberlainNR507 / NR 507 Final Exam (Latest 2021): Advanced Pathophysiology - Chamberlain

NR-507 Advanced Pathophysiology

NR507 Final Exam Review

How are vaccines formed?

- 1) Weakening the virus: reproduce poorly inside the body but replicate enough to

produce memory B cells.

-can’t be given to those with low immunity

2) Inactivate the virus: Kill the virus with a chemical body can still "see" the virus and can

protect against disease.

+ can be given to people with low immunity

-may have to give several doses

3) Use part of the virus: ex (hep B) take the protein that resides on the surface of the

virus, increase immune response to one part of the virus.

4) Bacteria: Produce toxins if inactivated a toxoid is produced and can be given. (ex.

tetnus)

Populations at risk for getting systemic fungal infections and parasitic infections

- IMMUNOCOMPROMISED

- IMMUNOSUPPRESSED

- POOR/ DISADVANTAGED

Systemic manifestations of infection

- fever, tachycardia, chills, weakness, headache, malaise, anorexia, nausea

mechanism responsible for the increase in antimicrobial resistance worldwide

- 1) lack of entry- decreased cell permeability

2) greater exit- active efflux

3) enzymatic inactivation of the antibiotic

4) altered target- modification of drug receptor site

5) synthesis of resistant metabolic pathway